Virtual Screening of Hepatitis B Virus Pre-Genomic RNA as a Novel Therapeutic TargetArticle Published on 2023-02-142023-06-12 Journal: Molecules [Category] B형 간염, [키워드] Drug discovery Hepatitis B virus molecular dynamics RNA virtual screening. [DOI] 10.3390/molecules28041803 PMC 바로가기
N6-methyladenosine Modification of Hepatitis B Virus RNA in the Coding Region of HBxArticle Published on 2023-01-232023-06-13 Journal: International Journal of Molecular Sciences [Category] B형 간염, [키워드] HBV m6A modification primary hepatocyte. RNA [DOI] 10.3390/ijms24032265 PMC 바로가기
Ultrafast and absolute quantification of SARS-CoV-2 on food using hydrogel RT-LAMP without pre-lysisArticle Published on 2023-01-152022-11-16 Journal: Journal of hazardous materials [Category] SARS, 치료기술, [키워드] Absolute quantification acute respiratory syndrome amplification cold chain Cold chain food contact infection coronavirus faster Food industry hydrogel Hydrogel RT-LAMP isothermal amplification microbe offer POCT point-of-care quantification reproducibility reverse transcription RNA RNA extraction RT-LAMP SARS-CoV-2 sensitivity specificity stability Surveillance Ultrafast detection. virus [DOI] 10.1016/j.jhazmat.2022.130050 PMC 바로가기
Multiple ligation-Assisted recombinase polymerase amplification for highly sensitive and selective colorimetric detection of SARS-CoV-2Article Published on 2023-01-152022-11-15 Journal: Talanta [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome amplification Analysis Bacterial colorimetric detection Colorimetric sensing conditions coronavirus detection system diagnosing disease Diseases effective Genome isothermal isothermal amplification limit of detection Multiple PK-probe point-of-care polymerase probe Pyrophosphate recombinase polymerase amplification Recombinase polymerase amplification (RPA) RNA robust SARS-CoV-2 SARS-CoV-2. selective sensitivity [DOI] 10.1016/j.talanta.2022.123835 PMC 바로가기
Inspection on the Mechanism of SARS-CoV-2 Inhibition by Penciclovir: A Molecular Dynamic StudyArticle Published on 2022-12-262023-07-11 Journal: Molecules [Category] COVID19(2023년), [키워드] drug Gromacs19 molecular dynamic simulations Nsp12 Nucleotide analog. Penciclovir RNA SARS-CoV-2 [DOI] 10.3390/molecules28010191 PMC 바로가기
SARS-CoV-2 RNA Is Readily Detectable at Least 8 Months after Shedding in an Isolation FacilityArticle Published on 2022-12-212023-07-10 Journal: mSphere [Category] COVID19(2023년), [키워드] COVID-19 Genome sequencing relic RNA RNA SARS-CoV-2 surface samples virus. [DOI] 10.1128/msphere.00177-22 PMC 바로가기
Defective Interfering Particles with Broad-Acting Antiviral Activity for Dengue, Zika, Yellow Fever, Respiratory Syncytial and SARS-CoV-2 Virus InfectionArticle Published on 2022-12-212023-07-10 Journal: Microbiology Spectrum [Category] COVID19(2023년), [키워드] antiviral therapy Chromatography coronavirus Defective Interfering Particle defective viral genome dengue virus purification respiratory syncytial virus RNA SARS-CoV-2 Yellow Fever virus. Zika virus [DOI] 10.1128/spectrum.03949-22 PMC 바로가기
Application of a high-throughput quantitative PCR system for simultaneous monitoring of SARS-CoV-2 variants and other pathogenic viruses in wastewaterArticle Published on 2022-12-202022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] acute respiratory syndrome Alpha variant analyzed application applied assays can be used collected Community coronavirus coronavirus disease COVID-19 delta variant demonstrated detect eight epidemiologically FIVE Health High-throughput qPCR highlighting increase Japan L452R labor-intensive likelihood Mie N501Y nine nucleotide nucleotide substitution pathogenic virus pathogenic viruses Pathogenic viruses, SARS-CoV-2 Patient PCR positive prevalent qPCR quantitative PCR quarantine reported RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 variant separated Surveillance target tested time-consuming Treatment virus viruses Volume wastewater Wastewater. Yokkaichi [DOI] 10.1016/j.scitotenv.2022.158659 PMC 바로가기
Reverse transcriptase-free detection of viral RNA using Hemo Klentaq DNA polymeraseArticle Published on 2022-12-152022-11-15 Journal: Analytical biochemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] affected amplification Analysis can be used caused comparable COVID-19 Degraded RNA demonstrated determine DNA polymerase Efficiency freeze-thaw cycles limitations Nasopharyngeal swab Nearby Nearby primers overcome pandemic patients PCR polymerase chain polymerase chain reaction Primers provide provided reliability reverse transcriptase Reverse transcriptase activity reverse transcription RNA RT-PCR SARS-CoV-2 SARS-CoV-2 detection target transcriptase Viral RNA Viral RNA. [DOI] 10.1016/j.ab.2022.114960 PMC 바로가기
Nucleoside Analogs and Perylene Derivatives Modulate Phase Separation of SARS-CoV-2 N Protein and Genomic RNA In VitroArticle Published on 2022-12-032023-07-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), [키워드] nucleocapsid protein phase separation RNA SARS-CoV-2 small-molecule antivirals. [DOI] 10.3390/ijms232315281 PMC 바로가기